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. 2018 Sep 10;10:270. doi: 10.3389/fnagi.2018.00270

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Copyright © 2018 Bangen, Werhane, Weigand, Edmonds, Delano-Wood, Thomas, Nation, Evangelista, Clark, Liu and Bondi.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Scatterplots of correlations between cognitive composite scores (z-scores) and regional cerebral blood flow (in units of milliliters per 100 g of tissue per minute). (A) Depicts the correlation between memory performance and left hippocampal CBF and (B) the correlation between executive function/processing speed and inferior parietal CBF (all p’s < 0.05). These significant associations were maintained controlling the FDR at 0.05. When partial correlation analyses were performed adjusting for diabetes status, the association between executive function/processing speed and regional CBF remained statistically significant (p < 0.05) whereas the association between memory and regional CBF was no longer significant.