Table 1.
Demographic and neuropsychological characteristics by T2DM status.
Nondiabetic (n = 38) |
T2DM (n = 11) |
F or χ2 | p | Effect size | |
---|---|---|---|---|---|
Demographics∗ | |||||
Age, years | 73.6 (5.9) | 72.3 (2.8) | 0.49 | 0.486 | = 0.010 |
Education, years | 17.0 (1.7) | 16.6 (2.4) | 0.24 | 0.627 | = 0.005 |
Sex, M:F | 13:25 | 8:3 | 5.17 | 0.023 | φc = 0.325 |
FSRP (%)∗∗ | 10.1 (7.9) | 13.4 (7.8) | 1.47 | 0.232 | = 0.030 |
Pulse pressure, mmHg | 50.5 (11.2) | 56.2 (16.1) | 1.86 | 0.179 | = 0.038 |
Current smoker (%) | 5.3 | 9.1 | 0.22 | 0.641 | φc = 0.067 |
History of cardiovascular disease (%) | 5.3 | 9.1 | 0.22 | 0.641 | φc = 0.067 |
History of hypertension (%) | 52.6 | 100.0 | 8.24 | 0.004 | φc = 0.410 |
History of atrial fibrillation (%) | 10.5 | 9.1 | 0.02 | 0.890 | φc = 0.020 |
GDS | 3.6 (3.9) | 6.1 (3.7) | 3.31 | 0.075 | = 0.069 |
Cognitive measures∗∗∗ | |||||
Mean (SD) | |||||
Global cognition (DRS total score) | 140.5 (3.4) | 138.3 (4.5) | 0.94 | 0.338 | = 0.021 |
Memory composite | 0.18 (0.8) | -0.78 (0.9) | 5.80 | 0.020 | = 0.117 |
Executive function/processing speed composite | 0.20 (0.7) | -0.83 (1.1) | 11.72 | 0.001 | = 0.218 |
T2DM, type 2 diabetes mellitus; SD, standard deviation; FSRP, Framingham stroke risk profile (D’Agostino et al., 1994); GDS, geriatric depression scale; DRS, Mattis dementia rating scale (Mattis, 1988).
∗Data are mean and standard deviation in parentheses unless otherwise noted.
∗∗Modified FSRP omitting diabetes.
∗∗∗DRS total score is a raw score (maximum possible score = 144); memory and executive function/processing speed composite scores are z scores. Results for the group comparisons on DRS and memory and executive function/processing speed composite scores are from analysis of covariance (ANCOVA) models adjusted for age, sex, and education.