Skip to main content
. 2020 Feb 19;2:23. Originally published 2018 Apr 26. [Version 3] doi: 10.12688/gatesopenres.12817.3

Table 7. Costs of moving current product candidates through the pipeline from their current phase.

Archetype Preclinical
($, millions)
Phase 1
($, millions)
Phase 2
($, millions)
Phase 3
($, millions)
Total
($, millions)
Simple vaccine 301.50 88.92 561.08 4930.42 5881.92
Complex vaccine 83.00 22.62 132.35 912.93 1150.90
Unprecedented vaccine 431.60 156.62 768.77 616.45 1973.42
Simple NCE 106.60 52.33 186.92 901.48 1246.75
Complex NCE 250.00 175.60 131.37 220.39 777.37
Simple repurposed drug - - 185.60 469.93 655.53
Complex repurposed drug 135.00 86.35 134.22 187.24 542.81
Simple biologic 33.50 6.70 40.58 172.36 253.14
Complex biologic 66.40 6.59 46.13 217.96 337.09
Concept &
Research
Feasibility &
Planning
Design &
Development
Validation
Diagnostic, assay
development
6.00 26.76 91.33 180.82 304.91
Diagnostic, simple
platform development
9.00 25.89 3025.46 100.31 3160.66
Other products 6.00 8.82 13.63 35.81 64.27
Total 1412.00 657.61 5316.86 8948.82 16348.79