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. 2020 Feb 19;2:23. Originally published 2018 Apr 26. [Version 3] doi: 10.12688/gatesopenres.12817.3

Table 9. Sensitivity analysis varying effect of changes in probability of success and cost of development per phase.

Parameters Percentage change from baseline Estimated cost
($, millions)
Estimated number
of product launches
Baseline 16348.8 128
Probability of
success
Low (-10%) 14873.3 89
High (+10%) 17981.7 160
Average cost per
phase
Low (-10%) 14713.9 -
High (+10%) 17983.6 -
Combined Low (-10% for both parameters) 13385.9 89
Intermediate 1 (Cost+10%, Probability
of success -10%)
16360.6 89
Intermediate 2 (Cost-10%, Probability of
success +10%)
16183.6 160
High (+10% for both parameters) 19779.9 160