Fig. 2.
Computational model design. A: schematic of the cortical column showing the different populations of cells across layers 1–6. Each color denotes a specific cell type in the column characterized on the basis of firing behavior. Depth and width of the cortical column were ~2,000 and ~400 µm, respectively. RS, regular spiking pyramidal neurons; FRB, fast rhythmic bursting pyramidal neurons; LTS, low-threshold spiking interneurons; IB, intrinsic bursting tufted pyramidal cells; TCR, thalamocortical relay cells; nRT, reticular thalamic nuclei cells. B: intracolumnar synaptic connectivity map showing both excitatory (glutamate: NMDA and AMPA) and inhibitory (GABAA) connections (Traub et al. 2005). E and I, excitatory and inhibitory neurons, respectively.