Table 2.

Phosphorus metabolites measured by ³¹P-MRS and intramyocellular lipid concentration ([IMCL]) by ¹H-MRS

Parameter	NGT	T2DM	P Value
[Pi], mM	2.80 ± 0.57	2.79 ± 0.41	0.93
[ATP], mM	7.18 ± 0.6	6.37 ± 1.05	0.02
[PCr], mM	28.6 ± 3.2	24.6 ± 2.4	0.002
[PCr]conv*, mM	32.5 ± 1.7	32.2 ± 4.1	0.82
[PDE], mM	3.11 ± 0.82	4.04 ± 0.98	0.02
[PDE]conv*, mM	3.72 ± 1.05	5.35 ± 1.6	0.005
pH	7.00 ± 0.03	7.00 ± 0.05	0.99
[Cr], mM	21.8 ± 5.6	19.7 ± 2.5	0.28
[ADP], µM	33 ± 9	31 ± 6	0.45
[ADP]conv**, µM	26 ± 8	35 ± 9	0.03
[IMCL]***, mmol/kg	6.87 ± 1.15	8.99 ± 1.46	0.004

^*[PCr]_conv and [PDE]_conv use the ratio of the desired metabolite to the amplitude of ATP × [ATP], using the assumption that [ATP]_conv = 8.2 mM.

^**[ADP]_conv assumes [ATP]_conv = 8.2 mM and [PCr] + [Cr] = 42.5 mM.

^***Determined in a subset of 9 NGT and 8 T2DM subjects.