Growth curves demonstrate absence of general health phenotype of NKCC1-DFX mice. Mice were weighed every 3 days for 3 wk and weekly thereafter until 84 days old or 12 wk of age. Weights were separated by sex and genotype after postnatal day P21. Red curves, NKCC1 wild-type mice; blue curves, NKCC1-DFX mice. F, female; M, male; NKCC1, Na+-K+-2Cl− cotransporter-1.