Table 1.
Effect of sex on acid-base parameters
| Parameters | Female | Male | P Value |
|---|---|---|---|
| Food intake, g | 8.9 ± 0.9 (12) | 9.6 ± 1.2 (12) | NS |
| Food intake, g/g body wt | 0.41 ± 0.04 (12) | 0.33 ± 0.04 (12) | <0.01 |
| Body weight, g | 22.2 ± 1.5 (12) | 29.1 ± 1.6 (12) | <0.01 |
| Plasma Na+, mmol/l | 147 ± 3 (12) | 148 ± 3 (12) | NS |
| Plasma K+, mmol/l | 3.9 ± 0.4 (12) | 4.2 ± 0.4 (12) | NS |
| Plasma HCO3−, mmol/l | 20.0 ± 3.1 (22) | 19.6 ± 2.2 (29) | NS |
| Urine ammonia, µmol/day | 72 ± 23 (11) | 46 ± 19 (9) | <0.01 |
| Urine ammonia, µmol/g body wt/day | 3.2 ± 0.9 (11) | 1.6 ± 0.7 (9) | <0.01 |
| Titratable acid, µmol/day | 53 ± 26 (11) | 74 ± 20 (9) | NS |
| Titratable acid, µmol/g body wt/day | 2.40 ± 1.16 (11) | 2.44 ± 0.67 (9) | NS |
| Net acid excretion, µmol/day | 125 ± 35 (11) | 120 ± 28 (9) | NS |
| Net acid excretion, µmol·g−1 body wt·day−1 | 5.63 ± 2.09 | 4.09 ± 0.88 (9) | <0.02 |
| Urine pH | 6.40 ± 0.18 (12) | 6.36 ± 0.14 (12) | NS |
Results are reported as means ± SE. The number of mice is shown in parentheses. NS, not significant.