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. 2018 Apr 18;315(2):F313–F322. doi: 10.1152/ajprenal.00065.2018

Fig. 2.

Fig. 2.

Inner medullary collecting duct (IMCD) principal cells label positively for proliferating cell nuclear antigen (PCNA) during early lithium treatment. Shown are representative images from kidney inner medullary tissue (IM-3) stained for the proliferation marker PCNA (green) and the renal principal cell marker, aquaporin-4 (AQP4) (red) in untreated rats (A), 1-wk lithium-treated rats (B), 2-wk lithium-treated rats (C), and 12-wk lithium-treated rats (D). Nuclei are stained blue with DAPI; n = 3.