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Endogenous RNA worms in vivo. (A) Endogenous RNA was labeled by fluorescent-UTP and the RGC axons were labeled by mGFP for visualization in vivo. The example shows the anterograde movement of the RNA worm toward the growth cone, followed by instantaneous condensation and fission into at least two separate RNA granules with globular morphologies. (B) Quantification of the speed of the RNA worm movement for (A). Scale bars, 5 μm for upper panel and 1 μm for lower panel of (A).
