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Effect of IL-37 treatment of obese mice on blood metabolites. After 22 weeks of HFD and 2 weeks of daily IL-37 or vehicle administration, metabolic markers were determined in plasma. a, adiponectin; b, leptin; c, cholesterol; d, triglycerides; e, IL-1Ra. *, p < 0.05; **, p < 0.01, as tested with ANOVA. n = 10 mice/group. Data are shown as means ± S.E. (error bars).
