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The corresponding mutation of Q511H in Cav2.1 and Q767H Cav3.1 suppress current density. A and B, representative traces (top) and I-V relationships (B) for WT (n = 8 cells) and mutant Cav2.1 channels (n = 9 cells, A) or WT (n = 11 cells) and mutant Cav3.1 channels (n = 14 cells, B). Voltage protocol was the same as in Fig. 2A. Results are from four independent experiments. Error bars represent S.E.
