Skip to main content
. 2018 Jul 19;293(37):14312–14327. doi: 10.1074/jbc.RA118.004450

Table 3.

Kinetic parameters defining the hydrolysis of different LPC species in the presence of their activating homologous LPA species fitted in the kinetic model (Fig. 8)

LPC/LPA species KD-LPC1 KD-LPAo KD-LPAa kcat slow kcat fast kcat fast/kcat slow
μm nm μm s1 s1
14:0 0.54 ± 0.08 62 ± 8 3.6 ± 0.2 0.067 ± 0.021 0.10 ± 0.05 1.5
16:0 0.7 ± 0.1 50 ± 3 2.5 ± 0.1 0.018 ± 0.011 0.21 ± 0.13 11.8
18:0 2.36 ± 0.03 56 ± 9 1.31 ± 0.6 0.020 ± 0.009 0.18 ± 0.05 8.8
18:1 1.71 ± 0.36 72 ± 9 2.05 ± 1.25 0.013 ± 0.003 0.043 ± 0.009 3.3
22:0/22:4 3.08 ± 0.05 38 ± 6 1.08 ± 0.15 0.004 ± 0.018 0.008 ± 0.003 2.1