Fig. 5.
%Leukocytes pre- and post-Plerixafor injection. For all animals, the preinjection percentage was calculated by averaging the leukocyte percentages from the 3 blood draws before injection. The postinjection percentage was calculated by taking the leukocyte percentage from a single blood draw at 3 different end points: 4 h postinjection for the control group (n = 3), 2 h postinjection for 1 experimental group (n = 3), and 6 h postinjection for the other experimental group (n = 3). An ANCOVA comparing the 3 groups on postinjection leukocyte percentages after controlling for baseline (preinjection) leukocyte percentages was statistically significant [F(2,5) = 6.33, P = 0.04], with a large effect size (partial η2 = 0.72). Planned orthogonal comparisons found no significant difference in the no. of mobilized leukocytes between the 2 experimental groups postinjection (P = 0.93), but the experimental animals had significantly higher leukocyte percentages than control animals postinjection (P = 0.04).