Table 2.
Plasma metabolic parameters
Maternal diet: | Normal Protein |
Low Protein |
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---|---|---|---|---|---|---|---|---|
Postwean diet: | Ad libitum |
Calorie restricted |
Ad libitum |
Calorie restricted |
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Sex (n): | Male (7) | Female (9) | Male (7) | Female (5) | Male (10) | Female (7) | Male (4) | Female (3) |
Plasma leptin, ng/ml (HE) | 1.50 ± 0.10 | 1.93 ± 0.19 | 1.53 ± 0.17 | 1.41 ± 0.14 | 1.25 ± 0.05 | 1.97 ± 0.32 | 1.95 ± 0.55 | 1.55 ± 0.18 |
Plasma glucose, mg/dl | 98.0 ± 5.01 | 114.7 ± 11.7 | 83.6 ± 6.8 | 79.4 ± 4.8 | 108.0 ± 5.5* | 84.3 ± 8.1* | 101.3 ± 16.9† | 84.7 ± 12.3 |
Plasma insulin, μU/ml | 4.39 ± 1.35 | 3.97 ± 0.92 | 4.43 ± 1.13 | 2.30 ± 0.07 | 3.82 ± 0.42 | 4.16 ± 1.13 (6) | 3.31 ± 0.41 | 3.13 ± 0.16 |
QUICKI index | 0.394 ± 0.014 | 0.391 ± 0.012†‡ | 0.404 ± 0.016§ | 0.443 ± 0.006†‡§ | 0.388 ± 0.009 | 0.398 ± 0.025‡ | 0.402 ± 0.016§ | 0.415 ± 0.013†‡§ |
Values shown as means ± SE. Where n differs from column heading, it is given in parentheses. Leptin RIA used human insulin in standard curve; antibody efficiency may be different for pig leptin. Log fasting plasma insulin/log fasting plasma glucose × 100; higher values reflect higher sensitivity. HE, human equivalent; QUICKI, qualitative insulin-sensitivity check index.
Significant data previously published (18).
P < 0.05, glucose, maternal diet effect in males only; QUICKI, postweaning diet effect in females only.
P < 0.05, QUICKI, sex effect.
P < 0.05, QUICKI, postweaning diet effect.