Fig. 1.

Baseline expression of circulating microRNAs (c-miRNAs) in plasma. At resting conditions before each weekly running session, c-miRNA levels in plasma (150 μl/sample) were measured by quantitative RT-PCR in volunteers participating in the fixed distance/variable intensity (n = 12; black bars) and fixed intensity/variable duration (n = 14; gray bars) portions of the study. Values are reported as relative levels based on the following formula: ($2^{{}^{–{\text{C}}_{\text{t}\text{m}\text{e}\text{a}\text{n}}}}$ × 10⁹), where C_t is threshold cycle. Data are presented as statistical means, and error bars reflect SEs.