. 2018 May 18;315(2):H348–H356. doi: 10.1152/ajpheart.00693.2017

Table 1.

Echocardiographic characteristics

	APJ^endo−/− TAC	APJ^endo−/− Sham	APJ^endo+/+ TAC	APJ^endo+/+Sham
n	8	7	6	6
Baseline
FS, %	39.1 ± 6.2	37.9 ± 3.7	39.0 ± 6.2	41.0 ± 4.2
LVIDd, mm	3.5 ± 0.3	3.5 ± 0.5	3.7 ± 0.3	3.4 ± 0.4
IVSd, mm	1.0 ± 0.1	1.0 ± 0.2	1.2 ± 0.2	1.1 ± 0.1
PWd, mm	1.0 ± 0.1	1.0 ± 0.2	1.2 ± 0.3	1.1 ± 0.2
Heart rate, beats/min	532 ± 58	559 ± 76	531 ± 38	492 ± 66
Week 4
FS, %	31.0 ± 12.5	42.6 ± 6.7	34.5 ± 10.1	37.8 ± 6.6
LVIDd, mm	3.9 ± 0.6	3.4 ± 0.4	3.7 ± 0.3	3.7 ± 0.9
IVSd, mm	1.0 ± 0.2	0.83 ± 0.2	1.1 ± 0.1^*	0.9 ± 0.05^*
PWd, mm	1.1 ± 0.2	1.0 ± 0.4	1.1 ± 0.2	0.7 ± 0.2
Heart rate, beats/min	538 ± 28	534 ± 38	535 ± 88	522 ± 54
Heart weight/body weight (10 wk)	7.3 ± 2.3	4 ± 0.45	5.8 ± 1.2	4.6 ± 0.45
Heart weight/tibia length (10 wk)^†	11.8 ± 3.2^*	6.3 ± 0.8^*	9.8 ± 1.6^*	7.5 ± 1.0^*
	APJ^myo−/− TAC	APJ^myo−/− Sham	APJ^myo+/+ TAC	APJ^myo+/+ Sham
n	3	4	5	3
Baseline
FS, %	36.1 ± 4.0	38.0 ± 3.3	37.6 ± 5.9	36.9 ± 3.1
LVIDd, mm	3.5 ± 0.1	3.6 ± 0.1	3.5 ± 0.5	3.4 ± 0.2
IVSd, mm	0.9 ± 0.1	0.65 ± 0.05	0.9 ± 0.2	0.73 ± 0.03
PWd, mm	0.9 ± 0.1	0.87 ± 0.09	1.1 ± 0.1	0.8 ± 0.1
Heart rate, beats/min	413 ± 15	529 ± 38	435 ± 70	508 ± 12
Week 4
FS, %	40.1 ± 10.6	38 ± 5.6	29.7 ± 8.2	37 ± 1.9
LVIDd, mm	3.5 ± 0.2	3.3 ± 0.3	3.4 ± 0.4	3.5 ± 0.2
IVSd, mm	0.9 ± 0.2	0.7 ± 0.08	1.1 ± 0.3	0.7 ± 0.06
PWd, mm	1.1 ± 0.2	0.8 ± 0.09	1.3 ± 0.2^*	0.9 ± 0.09^*
Heart rate, beats/min	444 ± 35	498 ± 70	421 ± 69	466 ± 35
Heart weight/body weight^†	6.7 ± 0.7	5.5 ± 0.7	9.2 ± 1.8	5.3±0.4
Heart weight/tibia length^†	9.0 ± 0.9	7.3 ± 0.8	12.2 ± 1.3^*	8.3±0.4^*

Values are expressed as means ± SD. TAC, transaortic constriction; FS, fractional shortening; LVIDd, left ventricular internal dimension at diastole; IVSd, interventricular septal thickness at diastole; PWd, posterior wall thickness at diastole.

P < 0.01 by post hoc Studentʼs t-test;

^†

P < 0.05 by ANOVA.