Table 3.
Rank | Drug | Condition (Reference) | Classification/Use |
---|---|---|---|
1 | Imipramine | Antidepressant | |
2 | Cinchonine | Alkaloid | |
3 | Sulmazole | Bronchoconstriction (60) | Adenosine receptor antagonist |
4 | Amrinone | Bronchoconstriction (44) | Phosphodiesterase inhibitor |
5 | Droperidol | Bronchoconstriction (73) | Dopamine antagonist |
6 | Canadine | Alkaloid | |
7 | Domperidone | Asthma (37) | Dopamine antagonist |
8 | Naringenin | Asthma (76) | Flavinoid |
9 | Amitriptyline | Bronchoconstriction (2) | Antidepressant |
10 | Tanespimycin | HSP90 inhibitor | |
11 | Diethylstilbestrol | Asthma* (97) | Nonsteroidal estrogen |
12 | 2-Aminobenzenesulfonamide | Carbonic anhydrase inhibitor | |
13 | Harmaline | Alkaloid | |
14 | Furosemide | Asthma (48) | Diuretic |
15 | Cefotaxime | Antibiotic | |
16 | 3-Nitropropionic acid | Mycotoxin | |
17 | Furosemide | Asthma (48) | Diuretic |
18 | Boldine | Alkaloid | |
19 | Fulvestrant | Chemotherapy | |
20 | Levothyroxine sodium | Asthma* (9) | Synthetic thyroxine |
21 | Homatropine | Anticholinergic | |
22 | Sulfaquinoxaline | Antiprotazoal | |
23 | Terguride | Serotonin antagonist and dopamine agonist | |
24 | Naftifine | Antifungal | |
25 | Raubasine | Antihypertensive |
Rank is order of correlation. CMAP, connectivity map; HSP, heat shock protein.
Adverse effect.