Table 5.
Rank | Drug | Condition (Reference) | Classification/Use |
---|---|---|---|
6076 | Amodiaquine | Bronchoconstriction (15) | Antimalarial |
6077 | Sulfachlorpyridazine | Sulfonamide | |
6078 | Trichostatin A | Hyperresponsiveness (3) | Histone deacetylase inhibitor |
6079 | Lisuride | Anti-Parkinson reagent | |
6080 | Mephenytoin | Anticonvulsant | |
6081 | Nalbuphine | Opioid antagonist | |
6082 | Acetylsalicylsalicylic acid | Asthma* (87) | Aspirin impurity |
6083 | Tamoxifen | Asthma (67) | Estrogen receptor blocker |
6084 | Pioglitazone | Asthma (55) | PPAR agonist |
6085 | Trichostatin A | Hyperresponsiveness (3) | Histone deacetylase inhibitor |
6086 | Valproic acid | Hyperresponsiveness (68) | Anticonvulsant |
6087 | Bromperidol | Neuroleptic | |
6088 | Lomustine | Chemotherapy | |
6089 | Midecamycin | Antibiotic | |
6090 | Prestwick-664 | Unknown | |
6091 | Convolamine | Sensory nerve blocker | |
6092 | Trichostatin A | Hyperresponsiveness (3) | Histone deacetylase inhibitor |
6093 | Cotinine | Alkaloid | |
6094 | Berberine | Bronchoconstriction (71) | Alkaloid |
6095 | Trichostatin A | Hyperresponsiveness (3) | Histone deacetylase inhibitor |
6096 | Naftopidil | Alpha adrenergic blocker | |
6097 | Mianserin | Bronchoconstriction (43) | Antidepressant |
6098 | Valproic acid | Hyperresponsiveness (68) | Anticonvulsant |
6099 | Tretinoin | Hyperresponsiveness (49) | All-trans retinoic acid |
6100 | Trichostatin A | Hyperresponsiveness (3) | Histone deacetylase inhibitor |
Rank is order of correlation. CMAP, connectivity map; PPAR, peroxisome proliferator-activated receptor.
Adverse effect.