Fig. 4.
Lung and liver mRNA values. CPAP, continuous positive airway pressure; VT, tidal volume; VT15, VT for 15 min; Bud 1, budesonide 1 mg/kg; Bud 0.25, budesonide 0.25 mg/kg. Lung (A–E): mRNA for surfactant proteins A (SFTPA; A), SFTPB (B), SFTPC (C), and SFTPD (D). Aquaporin 5 (AQ5; E) and epithelial sodium channel (ENaC; F) mRNA in the lung tissue. G: ATP-binding cassette sub-family A member 3 (ABCA3) transporter mRNA in lung. Liver (H–K): proinflammatory cytokine monocyte chemoattractant protein-1 (MCP-1; H) and IL-1β mRNA (I) in liver tissue. Acute-phase response genes serum amyloid A3 (SAA3; J) and chitinase-3-like protein-1 (CHI3L1; K) mRNA responses in the liver. Values are means ± SE with unventilatedcontrol (UVC) set at 1; n = 5–8 animals/group. +P < 0.05 vs. UVC; *P < 0.05 vs. CPAP + Saline; tP < 0.05 vs. VT15 +Saline.