Table 1.

Budesonide values and physiological variables

					Budesonide
Groups	n	BW, kg	VT 15 min, ml/kg	Hgb at Birth, mg/dl	Lung, ng/g	Plasma, ng/ml	Lung Weight, g/kg	V40/Lung Wt, ml/g	Dry Wt/Wet Wt, %Original
CPAP + Saline	5	2.9	N/A	12.7 ± 0.4	N/A	N/A	40 ± 2+	1.1 ± 0.1+	9.5 ± 0.4*
CPAP + Bud 0.25 mg/kg	6	2.6	N/A	12.5 ± 0.6	19 ± 2	0.2 ± 0.04	32 ± 2*	1.7 ± 0.1+*	10.2 ± 0.2*
Fetal VT + Saline	7	3.1	11.2 ± 1.3	11.6 ± 0.5*+	N/A	N/A	36 ± 1+	0.5 ± 0.1*	10.4 ± 0.3*
Fetal VT + Bud 0.25 mg/kg	8	3.0	11.9 ± 0.8	13.5 ± 0.4	24 ± 5	0.2 ± 0.02	25 ± 2t*	0.7 ± 0.1+*	14.5 ± 0.7+t
Fetal VT + Bud 1.0 mg/kg	7	2.7	13.2 ± 0.9	13.6 ± 0.4	84 ± 12t	0.8 ± 0.1t	21 ± 1t+*	0.9 ± 0.1+*t	15.7 ± 0.7+t
Unventilated controls	5	2.8	N/A	14.2 ± 0.5	N/A	N/A	28 ± 2	0.3 ± 0.1	11.8 ± 0.2t

Values are means ± SE. BW, body weight; V_T, tidal volume; V40, volume at 40 cmH₂O; CPAP, continuous positive airway pressure; Bud, budesonide; N/A, not analyzed.

⁺P < 0.05 vs. Controls;

^*P < 0.05 vs. CPAP + Saline;

^tP < 0.05 vs. Fetal V_T +Saline.