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. Author manuscript; available in PMC: 2019 Jul 1.
Published in final edited form as: NanoImpact. 2018 Feb 21;11:82–91. doi: 10.1016/j.impact.2018.02.007

Figure 6.

Figure 6

The inhibition of caveolae/raft-mediated endocytosis prevented actin microfilament alignment. Confluent layer of HUVEC cells were treated with 25 μM caveolae/raft-mediated endocytosis inhibitor, Nystatin for 2 hours prior to 2-hour PS nanoparticle exposure at 2.18 μg/mL or 0.66 μg/cm2. HUVEC after exposure to 20 nm PS NPs, actin (G), nucleus and PS NPs (H). HUVEC pretreated with Nystatin after exposure to 20 nm PS NPs, actin (E), nucleus and PS NPs (F). The 20 nm PS NPs-induced actin alignment was prevented by inhibiting the caveolae/raft-dependent endocytosis (E). Mean ± standard deviation of the sample. Date were analyzed with one way ANOVA, * denotes significant difference between comparisons, n = 20, p < 0.05.