Supplemental Figure 6.

Original: Overexpression of DN-RabA2A Induces Aggregates of PIN2 but Not PIN1.

(A) and (B) The 20 µM DEX-induced overexpression of DN-RabA2A does not change the PIN1 protein localization.

(C) and (D) The 20 µM DEX-induced overexpression of DN-RabA2A significantly increases PIN2 internalization, as visualized by the intracellular vesicles.

(E) to (G) Stable overexpression of DN-RabA2A does not change the PIN1 polarity.

(H) to (J) Stable overexpression of DN-RabA2A results in enhanced PIN2 agglomerations, which are colocalized with the DN-RabA2A vesicles (white arrowheads). Images are representative of three repeats. Bars = 10 µm. Note: (A) and (B) (boxed in red) were incorrectly duplicated from Figures 1D and 1E, respectively, of the main manuscript, and the labels are incorrect in the above supplemental figure.