Fig. 5.

A stable in vivo E2-Luc tumor line was established by series of in vivo passages from the luciferase-positive bright tumor tissue of BALB/c mice (#3 mouse in Fig. 4, was assigned as passage 0, P0). Luminescence-positive tumor tissues were transplanted from passage 1–4 (P1–4). BLI images were obtained (A) at the indicated days. Arrows indicated the mouse was selected for tumor transplantation. (B) Luciferase intensity of different passages (P1–4) tumors from (A) was quantified. (C) The tumor growth curve of different generations (E2 parent tumor, E2-Luc tumor P0–5) was shown on. Data represent means ± SD.