Figure 4.

Characterization of crowding effects. The plot depicts important physical quantities available from our model for the same parameters as in Fig. 3. (a) The density of motors on the MT is shown. Because kinesin-1 is a dimer, $\rho =1/2$ implies that the lattice is fully decorated with motors. (b) The fraction of detachment events that are due specifically to motor-induced detachment is shown. Even at low concentrations around 7 nM, facilitated dissociation is as prominent as spontaneous detachment. (c) The motor current on the MT, i.e., the number of motors passing over a lattice site per unit time, is shown. (d) The landing rate of motors on the MT (orange: experimental data (18), blue: mean-field results), assuming that a single lattice site is sufficient for the landing of a motor, is shown. The agreement is worse than for the original model (Fig. 3d). To see this figure in color, go online.