Figure 4.

Cytosolic Ca transient in the cell interior $\left(c_i\right)$ and boundary $\left(c_b\right)$ as a function of time. Here, the cell is paced for 100 beats to reach a steady state, after which we plot the Ca concentrations and membrane voltage. In (A), CL = 500 ms, and in (B), CL = 250 ms. For (B), the voltage trace corresponds to the beats indicated by the black horizontal line. The APD at which a large Ca release occurred is indicated with a red arrow. To see this figure in color, go online.