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. 2018 Sep 11;5(4):ENEURO.0283-18.2018. doi: 10.1523/ENEURO.0283-18.2018

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Copyright © 2018 Städele et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

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Figure 8. — Slow ionic conductances determine the effectiveness of ectopic APs on burst activity. A, Burst activity of three models with an I_KS time constant of 2 s. siAP frequency was varied from 7, to 5, to 3 Hz, and compared to 0 Hz (no firing). siAPs are depicted in black, sensory burst APs are highlighted in green. Note that decreasing siAP ff. increased burst duration (gray area). For better visualization, only burst starts and ends are shown. B–D, Analysis of changes in burst structure for different I_KS time constants at different siAP frequencies. B, Burst duration. C, Number of spikes per burst. D, Average intraburst ff.