Figure 2.

L-selectin is a determinant of early oxidative stress in the injured cord. Immunoblotting was performed on homogenates of uninjured (UN) and injured (SCI) cords from WT and L-selectin KO mice at 3 d post-SCI. All values were normalized to β-actin. By immunoblotting, MDA was reduced in L-selectin KO mice by 51% compared to WT mice after SCI (*p = 0.026, t₍₈₎ = 2.73). N = 3/genotype for UN and N = 5/genotype for SCI. Unpaired two-tailed Student’s t test. For UN, p = 0.98, t₍₄₎ = 0.02.