Figure 3.
There were no developmental changes in axonal diameter or g-ratios of myelinated axons in the CCFM. A, Schematic showing a cross-section of a myelinated axon. G-ratios were calculated by obtaining a measurement of the inner axon area and the whole fiber area. B, Relative myelin thickness, as measured by g-ratio, did not change between pre-adolescence and adolescence (n = 4 per group, t(5.43) = 0.78, p = 0.47). C, A two sample Kolmogorov–Smirnov test showed that axon diameter distribution does not change from pre-adolescence to adolescence (p = 0.1708). Data are expressed as mean ± SEM. Illustrations were created by modifying images purchased in the PPT Drawing Toolkits-BIOLOGY Bundle from Motifolio, Inc.