Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 Aug 21;5(4):ENEURO.0228-18.2018. doi: 10.1523/ENEURO.0228-18.2018

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2018 Heiss et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

PMC Copyright notice

Figure 2. — LH activation induces continuous wakefulness for at least 4 h. Hourly percentage of time spent in W (A), NREM (B), and REM sleep (C) and hourly bout duration for W (A’) and NREM (B’) after injection of either CNO (red) or SAL (black). Asterisks denote significant difference between CNO and SAL treatment for the respective hour when a significant treatment × time interaction was found (p ≤ 0.047, n = 9; two-way repeated measures ANOVA, Bonferroni post hoc t test). B’’, No significant change in NREM δ power was observed after the prolonged W induced by CNO injection (n.s., n = 6, two-way repeated measures ANOVA). Arrow at bottom left of abscissa indicates time of dosing at ZT12.