Table 4.

Multi-class Classifications of Dementia.

Multi dementia types
Name	Sample	Classification	Measures	ROIs	Acc	SS (FTD)	SP (FTD)	AUC (FTD)
Klöppel et al., 2015	12 FTD	SVM	VBM-GM volume	Whole-brain				0.78
	122 AD	Separate test cohort
	4 DLB
	18C
Koikkalainen et al., 2016	92 FTD	Disease State Index (DSI)	Volumes	Whole-brain parcellation	50.4
			VBM-GM concentration		65.1
		10-fold CV	TBM		64.3
			Manifold learning	Hippocampus and frontotemporal lobe	50.4
			ROI-based grading		58.3
			Vascular burden- WMH, cortical and lacunar infarcts volumes		32.7
	223 AD
			All features		70.6	62	95
	47 DLB
	24 VaD
	118 C
Tong et al., 2017	92 FTD	RUSBoost	Volumes	Whole-brain parcellation	58.6
					66.6
					70
		10-fold CV	Grading
			Combination
	219 AD
	47 DLB
	24 VaD
	118 C
Vemuri et al., 2011	47 FTD	Differential-STAND	GM density	Whole brain		84.4	93.8
	48 AD	LOOCV
	20 DLB
	21 C