Table 5.

PPA classifications.

Name	Sample	Classification	Measures	ROIs	Acc	SS	SP	AUC	Acc	SS	SP	AUC	Acc	SS	SP	AUC
					nfvPPA vs Controls				lvPPA vs Controls				svPPA vs Controls
Bisenius et al., 2017	16 nfvPPA	SVM	VBM-GM density	Whole-brain ROI (a priori from meta-analyses)	91	88	94	0.94	95	91	100	0.95	97	94	100	0.97
					84	81	88	0.90	82	82	82	0.91	100	100	100	1
	17 svPPA	LOOCV
	11 lvPPA
	20 C
Wilson et al., 2009	32 nfvPPA	SVM	GM volume	PCA	89.1	87.5	90.6	0.941	100	100	100	1	100	100	100	1
	38 svPPA	2-level CV
	16 lvPPA
	115 C
					svPPA vs nfvPPA				lvPPA vs svPPA				lvPPA vs nfvPPA
Bisenius et al., 2017	16 nfvPPA	SVM	VBM-GM density	Whole-brain ROI (a priori from meta-analyses)	78	81	75	0.88	95	100	91	0.93	55	64	45	0.59
	17 svPPA	LOOCV
					78	81	75	0.87	95	100	91	0.91	64	73	55	0.64
	11 lvPPA
	20 C
Wilson et al., 2009	32 nfvPP	SVM	GM volume	PCA	89.1	84.4	93.8	0.964	93.8	93.8	93.8	0.984	81.3	81.3	81.3	0.879
	38 svPP	2-level CV
	16 lvPPA
	115 C
					PPA (svPPA and nfvPPA) vs Controls
					Acc				SS				SP
Chow et al., 2008	14 PPA	Logistic regression	Volumes	L anterior temporal	90.9				78.6				96.7
	30 C
					bvFTD vs others				svPPA vs. others				nfvPPA vs others
					Acc	SS	SP		Acc	SS		SP	Acc	SS		SP
Tahmasian et al., 2016	11 bvFTD	SVM	VBM-GM volume	A priori based on the NDH	72.5	45.4	82.7		92.5	50		97.5	82.5	0		94.2
	4 svPPA	LOOCV
	5 nfvPPA
	20 AD