Table 4.

Risk factors associated with PSD by gender.

Factors	Univariate model		Multivariate model 1		Multivariate model 2
	HR (95% CI)	p	Adjusted HRa (95% CI)	p	Adjusted HRb (95% CI)	p
Female
Age	1.00 (0.93–1.07)	0.990
TDQ	1.21 (1.03–1.42)	0.021	1.30 (1.09–1.56)	0.004
NIHSS	1.33 (1.02–1.74)	0.037	1.70 (1.16–2.50)	0.007
IADL	0.89 (0.79–1.01)	0.080
MMSE	0.98 (0.82–1.17)	0.836
Male
Age	1.02 (0.93–1.13)	0.657
TDQ	1.20 (1.07–1.34)	0.002	1.18 (1.04–1.33)	0.009	1.20 (1.07–1.34)	0.002
NIHSS	1.24 (0.95–1.63)	0.111
IADL	0.94 (0.82–1.07)	0.352
MMSE	0.73 (0.54–0.98)	0.035	0.82 (0.64–1.05)	0.111

Abbreviations: HR: Hazard ratio; CI: Confidence interval; TDQ: Taiwanese Depression Screening Questionnaire; NIHSS: National Institutes of Health Stroke Scale; IADL: Instrumental activities of daily living scale; MMSE: Mini-mental status examination; PSD: Poststroke depression.

^aFemale multivariate model 1 included TDQ and NIHSS, and male model 1 included TDQ and MMSE.

^bMale multivariate model 2 included TDQ only.