Table 1.
Association between deletions 1p and other factors
| Characteristics | No deletion N=904 |
Deletion 1p22 N=176 |
P* | Deletion 1p32 N=85 |
P* | |
|---|---|---|---|---|---|---|
| Beta2 microglobulin | Median (IQR) | 3.2 (2.3–5.1) | 3.5 (2.5–6.4) | 0.07 Wilcoxon | 3.8 (2.7–7.2) | 0.02 Wilcoxon |
| ISS N(%) | 1 | 239 (35.7) | 36 (29.0) | 0.01 | 13 (20.6) | 0.03 |
| 2 | 254 (37.9) | 39(31.5) | Chi2 | 26(41.3) | Chi2 | |
| 3 | 177(26.4) | 49 (39.5) | 24(38.1) | |||
| t(4;14) N(%) | No | 706(91.2) | 116(74.8) | <0.001 | 54(78.3) | 0.001 |
| Yes | 68(8.8) | 39 (25.2) | Chi2 | 15(21.7) | Chi2 | |
| Deletion 17 p N(%) | No | 686 (93.0) | 119(82.6) | <0.001 | 62 (82.7) | 0.002 |
| Yes | 52(7.1) | 25(17.4) | Chi2 | 13(17.3) | Chi2 | |
| Deletion 13 N(%) | No | 463 (56.3) | 53(33.3) | <0.001 | 29 (36.3) | 0.001 |
| Yes | 359 (43.7) | 106(66.7) | Chi2 | 51 (63.8) | Chi2 | |
| Bortezomib induction N(%) | No | 589 (65.2) | 107(60.8) | 0.27 | 48 (56.5) | 0.11 |
| Yes | 315(34.9) | 69 (39.2) | Chi2 | 37 (43.5) | Chi2 |
*
The comparisons are made versus the patients with no deletion 1p.