Fig. 21.
a) Schematic illustration of the application of BMSC-laden GelMA microspheres for osteogenesis and regeneration of injured bones in vitro and in vivo.228 b) Viability of BMSCs encapsulated in GelMA after 1 and 7 d of culture. Phalloidin/DAPI images of BMSCs cultured in GelMA after 2 and 4 weeks. c) Bone defect repair in vivo. Histomorphometrical analysis (%) of new bone formation and (E) osteoid (arrows) formation and total area in the defect zone (* p < 0.05). Reprinted with permission from ref. 228. Copyright 2016, John Wiley & Sons, Inc.