Table 2.
Oncological outcomes after an intersphincteric resection for patients with rectal cancer
| Study | Year | Sample size (n) | Tumor location from anal verge (cm) | Follow- up duration (mo) | PCRT (%) | R0 resection rate (%) | Length of distal resection margin (cm) | 5-Year local recurrence rate (%) | 5-Year overall survival rate (%) | 5-Year disease-free survival rate (%) |
|---|---|---|---|---|---|---|---|---|---|---|
| Braun [2] | 1992 | 63 | - | 80 | - | - | - | 11 | 62 | - |
| Kohler [11] | 2000 | 31 | 1.3 | 82 | 0 | - | 1.6 | 9.7 | 79 | - |
| Rullier [12] | 2001 | 21 | 4.5 | 30 | 10 | 98 | 2.3 | 2 | 85 (3 yr) | 85 (3 yr) |
| Tiret [6] | 2003 | 26 | 4.25 | 39 | 38.5 | 96.2 | 1.6 | 3.4 | 96 | - |
| Saito [7] | 2004 | 35 | 0-2 | 23 | 57.1 | 100 | 1.3 | 1 | - | - |
| Schiessel [14] | 2005 | 121 | 3 | 94 | 0 | 96.7 | - | 5.3 | 126.1 mo | - |
| Saito [15] | 2006 | 228 | 3.4 | 41 | 25 | 98.7 | - | 6.7 | 91.9 | 83.2 |
| Chamlou [18] | 2007 | 90 | 3.5 | 56.2 | 41 | 94.4 | 1.2 | 6.6 | 82 | 75 |
| Portier [17] | 2007 | 105 | 4.1 | 66.8 | 53.2 | 96 | 2.6 | 10.6 | 86.1 | 83.9 |
| Akasu [19] | 2007 | 106 | 3 | 41 | 0 | 97.2 | 1.2 | 7.3 (3 yr) | 95 (3 yr) | - |
| Weiser [21] | 2009 | 44 | <6 | 47 | 100 | 90 | 1.0 | 0 | 96 | 83 |
| Park [24] | 2011 | 210 | Lap (3.6), open (4.7) | 34 | Lap (7.7), open (1.3) | Lap (97.7), open (95) | Lap (1.5), open (1.4) | Lap (2.6), open (7.7) | - | Lap (82.1), open (77) |
| Laurent [27] | 2012 | 175 | <6 | 53 | 90.3 | 88 | 1.9 | 3.5 | 84 | 90 |
| Baek [25] | 2013 | 84 | Lap, (5.52); robotic, (4.39) | 31.5 | Lap, (32,4); robotic, (42.6) | Lap, (91.9); robotic, (97.9) | Lap, (1.6); robotic, (1.1) | Lap, (5.4); robotic, (6.4) | Lap, (90.7); robotic, (86.5) | Lap, (81.2); robotic, (80.6) |
| Saito [32] | 2014 | 199 | <5 | 78 | 24.6 | 80.4 | - | 19.7 (7 yr) | 78.3 | 66.7 |
PCRT, preoperative chemoradiotherapy; Lap, laparoscopic.