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PDZ-RhoGEF expression is increased in GBM. (A) IHC analysis of PDZ-RhoGEF expression in non-neoplastic brain and GBM biopsy samples (upper panel). Samples are representative of 36 matched biopsy samples on a tissue microarray. a, negative, score 0; b, minimum, score 1; c, moderate, score 2; d, strong, score 3. Neuropathology scoring of the percentage distribution of staining intensity of PDZ-RhoGEF in GBM patient specimens (lower panel).
