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. 2018 Aug 27;115(37):E8793–E8802. doi: 10.1073/pnas.1809841115

Fig. 6.

Fig. 6.

Interdependence of H3K9me2 and CHH methylation defects in kyp, suvh5, suvh6, and kyp/suvh5/6. (A) CHH methylation (mCAA, mCTA, mCTT, mCTC, mCAT, mCAC, mCCA, mCCC, and mCCT) levels at kyp/suvh5/6-dependent H3K9me2/H3 peaks in WT, kyp, suvh5, suvh6, and kyp/suvh5/6. ***P value <2.2e−16, **P value <1e−8 with Student’s t test. (B) Heatmap of normalized H3K9me2 levels in kyp/WT, suvh5/WT, suvh6/WT, and kyp/suvh5/6/WT plotted over kyp/suvh5/6-dependent CHH sites (mCAA, mCTA, mCTT, mCTC, mCAT, mCAC, mCCA, mCCC, and mCCT). (C) Proportions of CHH sites (mCAA, mCTA, mCTT, mCTC, mCAT, mCAC, mCCA, mCCC, and mCCT) in kyp/suvh5/6-dependent mCHH sites.