Majority-rule phylogram inferred from maximum-likelihood analysis of FPPS and TPS enzymes of M. histrionica (bold) with related IDS proteins of H. halys, TPS and IDS proteins of P. striolata, GPPS/TPS of I. pini, and other insect trans-(GPPS)/FPPS proteins. The maximum likelihood method was based on the Le and Gascuel (59) (LG G+I) model. Bootstrap values (n = 1,000 replicates) are shown next to each node. The tree is drawn to scale, with branch lengths measured in the number of substitutions per site. Proteins with known or putative TPS activity are highlighted by the gray box. The tree was rooted using a GGPPS from D. melanogaster. Full species names are listed in SI Appendix, Fig. S7.