Figure 2.

Performance of genetic risk classification based on genetic risk score in predicting combined outcome (end-stage kidney disease or 50% eGFR decline). (A) Survival analysis of time without combined outcome according to the tertile of genetic risk score. (B) Receiver operating curves for models predicting the 5-year risk of combined outcome using original clinical risk model and original clinical risk model plus genetic risk score. (C) Receiver operating curves for models predicting the 5-year risk of combined outcome using original clinical-pathologic risk model and the original clinical-pathologic risk model plus genetic risk score. Low genetic risk, genetic risk, score 4-5: middle genetic risk, genetic risk score 6: high genetic risk, genetic risk score 7-8. Original clinical risk model: clinical model from Xie et al. (19). Original clinical–pathologic risk model: clinical and pathologic model from Xie et al. (19).