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. 2018 Sep 11;11:5723–5731. doi: 10.2147/OTT.S161760

Figure 3.

Figure 3

The effect of IL-8 on expression of stemness genes.

Notes: (A) The levels of stemness-related genes were analyzed in sphere cells transfected with siIL-8 or siNC by qRT-PCR. **P<0.01, compared with control. (B) The mRNA levels of the indicated stemness-related genes in H446 cells treated with 100 ng/mL rh-IL-8. Data are expressed as mean ± standard error of the mean of three independent experiments. *P<0.05, **P<0.01, compared with control.

Abbreviations: ns, not significant; rh-IL-8, human recombinant IL-8; siIL-8, IL-8 siRNA; siNC, negative control oligonucleotide; uPAR, urokinase plasminogen activator receptor; qRT-PCR, quantitative reverse transcription PCR.