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. 2018 Sep 12;11:5797–5809. doi: 10.2147/OTT.S161280

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© 2018 Lv et al. This work is published and licensed by Dove Medical Press Limited

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Disruption of PPP5C expression results in cell cycle arrest in PCa cells.

Notes: (A) Flow cytometry analysis showing cell cycle distribution of DU145, PC3, and 22RV1 cells infected by Lv-shCon or Lv-shPPP5C. (B) Cell percentages in G0/G1, S, and G2/M of DU145, PC3, and 22RV1 cells treated as in (A) are analyzed statistically (^*P<0.05, ^***P<0.001). Con: no lentivirus-mediated shRNA; Lv-shCon: lentivirus-mediated non-silencing shRNA; Lv-shPPP5C: lentivirus-mediated non-silencing shPPP5C.

Abbreviations: PCa, prostate cancer; PPP5C, serine/threonine protein phosphatase 5.