Table 8. Biotransformation activities of PCM-CH2OH in rat and human female hepatocytes.
| Species | Activity (nmol/hour/g body weight)a) (relative activity)b) | |
|---|---|---|
| Hydroxylated-PCM to Carboxylated-PCM | Hydroxylated-PCM to Glucuronide | |
| Rat | 0.47 (1.0) | 0.32 (1.0) |
| Human | 0.88 (1.9) | 1.12 (3.5) |
a) Data represent mean value (n=2). b) Rat data were defined as 1.0.