Table 3.

Common adverse events experienced by ≥1% of patients receiving meropenem-vaborbactam in TANGO I

Adverse event	Meropenem-vaborbactam (n=272)	Piperacillin-tazobactam (n=273)
Headache	24 (8.8)	12 (4.4)
Diarrhea	9 (3.3)	12 (4.4)
Nausea	5 (1.8)	4 (1.5)
Asymptomatic bacteriuria	4 (1.5)	4 (1.5)
Catheter-site phlebitis	5 (1.8)	3 (1.1)
Infusion-site phlebitis	6 (2.2)	2 (0.7)
Urinary tract infection	4 (1.5)	4 (1.5)
Alanine aminotransferase increased	5 (1.8)	1 (0.4)
Aspartate aminotransferase increased	4 (1.5)	2 (0.7)
Pyrexia	4 (1.5)	2 (0.7)
Hypokalemia	3 (1.1)	4 (1.5)

Note: Data are presented as n (%).

Abbreviation: TANGO, Targeting Antibiotic Non-susceptible Gram-negative Organisms.