Fig. 2.

Quantitative analysis of Fn14 protein expression in patient-matched primary and recurrent GBM tumors. (A) Patient-matched primary and recurrent specimens were immunostained with an Fn14 antibody and stain intensity was quantitated using the Aperio imaging system. Each specimen is indicated by a black circle. Horizontal bars indicate the median (long bar) and interquartile (short bar) range. *P = 0.01 using 2-way ANOVA. (B) Fn14 staining intensity for the 8 sets of resected tumors is indicated. Colored lines are used for the 3 patients whose immunostaining results are included in Fig. 3 (patient #8, red line; patient #3, green line; patient #6, blue line).