TABLE 7.
Correlation of Clinical Variables With the Chordoma Grading System (P-values only)
| N (%) | Mean chordoma score | Sig. | |
|---|---|---|---|
| Number of complications | |||
| Mean (SD) | 0.6 (0.9) | .858 Spearman correlation | |
| 0 | 26 (62%) | 10.5 | |
| 1 | 6 (14%) | 11.7 | |
| 2+ | 10 (24%) | 10.4 | |
| Severe complicationa | |||
| No | 29 (69%) | 10.7 | .910 t-test |
| Yes | 13 (31%) | 10.5 | |
| Time to death | |||
| No | 38 (90%) | 10.3 | .531 Cox regression |
| Yes | 4 (10%) | 13.5 | |
| Cumulative survival | 78% | ||
| Mean survival (mo) | 121 | ||
| Mean follow-up (mo) | 60 (42) | ||
| Time to recurrence | |||
| No | 34 (81%) | 9.8 | .029 Cox regression |
| Yes | 8 (19%) | 14.3 | |
| Cumulative survival | 59% | ||
| Mean survival (mo) | 103 | ||
| Mean follow-up (mo) | 50 (39) | ||
| Change in KPS at 12 mo | |||
| Mean (SD) | 1 (11) | .534 Spearman correlation | |
| Worse | 6 (14%) | 10.3 | |
| Same | 22 (52%) | 11.3 | |
| Better | 14 (33%) | 9.7 | |
| Composite outcomeb | .005 Mann–Whitney | ||
*All significance values are from t-tests, Mann–Whitney, Spearman correlations, and Cox models.
aCerebrospinal fluid leak or major permanent deficit or cranial nerve palsy or reoperation for complication.
bTotal resection and no death/stroke/maj. deficit and no recurrence by 12 mo and KPS 12 > 70.