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. 2018 Aug 10;27(19):3449–3463. doi: 10.1093/hmg/ddy258

Figure 8.

Figure 8

Increased expression of components of Notch and Wnt signalings in skeletal muscle of Mdx;MyD88scko mice. Relative mRNA levels of (A) Notch ligands, (B) Notch receptors and (C) Notch target genes in GA muscle of 8-week-old Mdx;MyD88f/f and Mdx;MyD88scko mice. Relative mRNA levels of indicated (D) Wnt ligands, (E) Wnt receptors and (F) Wnt target gene, Axin-2, in Mdx;MyD88f/f and Mdx;MyD88scko mice. (G) Representative immunoblots showing protein levels of Wnt3a and Axin-2 in Mdx;MyD88f/f and Mdx;MyD88scko mice. (H) Relative fold change in protein levels of Wnt3a and Axin-2 in Mdx;MyD88f/f and Mdx;MyD88scko mice. N = 5 mice. Error bars represent s.d. *P-value < 0.05, **P-value < 0.01 and ***P-value < 0.001 from corresponding littermate Mdx;MyD88f/f mice by unpaired t-test.