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. Author manuscript; available in PMC: 2019 Dec 1.
Published in final edited form as: Int J Hyperthermia. 2018 Feb 22;34(8):1213–1224. doi: 10.1080/02656736.2018.1438672

Figure 3.

Figure 3.

Gross pathology along with H&E and vimentin stains created using sonication parameter sets F (panels a & b) and C (panels c & d). Vimentin stains for mesenchymal cells and is a surrogate for tissue viability. Panel b shows substantial damage of tissue beyond the focal region (panel b2, yellow arrowhead) even though H&E indicates intact tissue (panel a3 green arrowhead). In contrast, panel c shows structurally intact tissue around the focal region and panel d depicts viable tissue in this intact region (green and yellow arrowheads in panels c3 & d2 respectively).