Table 3A.
The immune processes and immune gene categories involved in differentially expressed intestinal mRNA for each stage.
| Compared group (DEG No.) | Immune process (Differential expressing gene No.) | Immune gene category |
|---|---|---|
| The early stages (3 weeks vs. 0 days) UP (40) |
Antigen processing and regulators (9); inflammatory cytokines and receptors (15); adapters, effectors and signal transducers (1); T/B cell antigen activation (9); other genes related to immune response (6); | HA1; HA2; MHC I; MHC I related; MHC II; macroglobulin; CCL; CCR; chemokine receptor; FAM; FGF and related; GVIN; IFN induced proteins and relevant; IIGP; IL21R; IL34; IL7R; granzyme; CD2; CD226; CD3; CD5; PKC; RGS; TCR; VTCN; CD200; GIAMP; NK-lysin; ubiquitin ligase. |
| The early stages (3 vs. 0 days) DOWN (11) |
Acute phase reactions (1); antigen processing and regulators (1); inflammatory cytokines and receptors (2); T/B cell antigen activation (3); other gene related to immune response (4) | Hemopexin; TGF, TGF receptor and related; integrin alpha; BCL; TCR; PTKs; CEBP; GIAMP; lymphocyte related; myeloid cell related. |
| The middle stages (5 vs. 3 weeks) UP (83) |
Acute phase reactions (9); pattern recognition (4); antigen processing and regulators (5); complement system (18); inflammatory cytokines and receptors (20); adapters, effectors and signal transducers (10); T/B cell antigen activation (3); other genes related to immune response (14). | Fibrinogen; macroglobulin; plasminogen; C-type lectin; fish-egg lectin; galectin; intelectin; CDK and related; C1q; C3; C5; C7; C8; C9; CFB; CFI; MASP; CCR; CFLAR; CXCR; EGF, EGFR and related; GVIN; IFN induced proteins and relevant; IRF; NFIL3; CD276; CIS; lysosomal protein; NFKBI and related; NLRC3; SCOCS (1-7); BCL; FCGBP; RGS; caspase; CEBP; hepcidin; HSP; myeloid cell related; oncogene; ubiquitin ligase. |
| The middle stages (5 vs. 3 weeks) DOWN (37) |
Pattern recognition (3); antigen processing and regulators (6); complement system (2); inflammatory cytokines and receptors (9); adapters, effectors and signal transducers (2); T/B cell antigen activation (2); other genes related to immune response (13). | LPS-anchor protein; LRR-containing proteins; CDK and related; MAF; MHC I related; TNF; TNR and related; C3aR; MASP; FAM; GVIN; IL34; IL4; IL7R; lysosomal protein; NLRC3; CD2; PIGR; GIAMP; HSP; ubiquitin ligase. |
| The late stages (7 vs. 5) UP (12) |
Pattern recognition (1); antigen processing and regulators (2); complement system (1); inflammatory cytokines and receptors (1); T/B cell antigen activation (1); other genes related to immune response (6). | HMG; CDC and related; MHC I related; C6; CCR; CD48; caspase; CD82; GIAMP; ubiquitin ligase. |
| The late stages (7 vs. 5 weeks) DOWN (44) |
Pattern recognition (5); antigen processing and regulators (2); complement system (1); inflammatory cytokines and receptors (5); adapters, effectors and signal transducers (14); T/B cell antigen activation (4); other genes related to immune response (13). | LPS-anchor protein; LRR-containing proteins; CDK and related; VEGF; C1q; CXCL; FGF and related; GVIN; IL20R; CD276; CIS; lysosomal protein; MAPK; MAPK related; NLRC3; PPARA; SOCS (1-7); BCL; NFAT; SEMA; caspase; GIAMP; HSP; oncogene; ubiquitin ligase; ubiquitin related. |