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. 2018 Jan 30;96(2):375–397. doi: 10.1093/jas/sky020

Table 5.

The least squares means (SE) and P-values for the markers associated (P ≤ 0.05) with midpoint metabolic weight and back fat using genotypic effect and additive and dominance models

Gene Name rs#1 Genotype Midpoint Metabolic Weight (kg) Back fat (mm)
P-value LSM ± SE a2 ± SE d3 ± SE P-value LSM ± SE a1 ± SE d2 ± SE
RRP1B rs43285609 AA 85.739 ± 0.381 -0.135 ± 0.321 0.312 ± 0.388 0.05 7.022 ± 0.183 0.019 ± 0.089 0.254 ± 0.109*
RRP1B rs43285609 GA 86.185 ± 0.381 7.257 ± 0.137
RRP1B rs43285609 GG 86.008 ± 0.381 6.984 ± 0.151
GALNT13 rs438856835 AA 85.883 ± 0.38 0.196 ± 0.962 0.828 ± 1.063 0.035 7.094 ± 0.13 -0.486 ± 0.274 0.77 ± 0.304*
GALNT13 rs438856835 CA 86.908 ± 0.38 7.378 ± 0.191
GALNT13 rs438856835 CC 86.275 ± 0.38 6.122 ± 0.555
SMARCAL1 rs208660945 CC 85.764 ± 0.382 -0.172 ± 0.297 0.219 ± 0.391 0.049 7.177 ± 0.174 0.111 ± 0.083 0.203 ± 0.109
SMARCAL1 rs208660945 CT 86.155 ± 0.382 7.269 ± 0.141
SMARCAL1 rs208660945 TT 86.109 ± 0.382 6.955 ± 0.148
LRRIQ3 rs42417924 CC 0.043 86.331 ± 0.38 -0.857 ± 0.742 -0.368 ± 0.806 7.171 ± 0.132 -0.013 ± 0.211 -0.187 ± 0.231
LRRIQ3 rs42417924 GC 85.107 ± 0.38 6.971 ± 0.17
LRRIQ3 rs42417924 GG 84.618 ± 0.38 7.145 ± 0.427
DPP6 rs110519795 AA 0.05 86.44 ± 0.381 -0.725 ± 0.308* 0.446 ± 0.395 7.178 ± 0.148 -0.062 ± 0.086 0.017 ± 0.112
DPP6 rs110519795 AG 86.161 ± 0.381 7.133 ± 0.142
DPP6 rs110519795 GG 84.99 ± 0.381 7.054 ± 0.18
DPP6 rs132717265 AA 85.689 ± 0.382 -0.393 ± 0.313 -0.015 ± 0.381 0.007 6.895 ± 0.164 -0.264 ± 0.086** -0.067 ± 0.107
DPP6 rs132717265 GA 86.068 ± 0.382 7.092 ± 0.138
DPP6 rs132717265 GG 86.476 ± 0.382 7.423 ± 0.159
PPM1K rs134225543 CC 0.018 85.78 ± 0.383 1.013 ± 0.727 0.673 ± 0.886 0.015 7.198 ± 0.129 -0.521 ± 0.207* 0.214 ± 0.253
PPM1K rs134225543 TC 87.465 ± 0.383 6.891 ± 0.194
PPM1K rs134225543 TT 87.806 ± 0.383 6.156 ± 0.424
CAST rs384020496 AA 87.727 ± 0.377 0.973 ± 0.518 -0.124 ± 0.751 0.014 7.465 ± 0.31 0.203 ± 0.15 0.277 ± 0.214
CAST rs384020496 GA 86.631 ± 0.377 7.539 ± 0.199
CAST rs384020496 GG 85.782 ± 0.377 7.058 ± 0.13
CAST rs133057384 AA 87.548 ± 0.38 0.827 ± 0.731 -0.102 ± 0.846 0.018 7.665 ± 0.42 0.307 ± 0.207 0.088 ± 0.24
CAST rs133057384 GA 86.619 ± 0.38 7.447 ± 0.179
CAST rs133057384 GG 85.894 ± 0.38 7.052 ± 0.13
CAST rs110711318 CC 85.843 ± 0.38 1.273 ± 0.831 -0.272 ± 0.968 0.017 7.058 ± 0.131 0.37 ± 0.233 0.045 ± 0.272
CAST rs110711318 TC 86.843 ± 0.38 7.473 ± 0.188
CAST rs110711318 TT 88.388 ± 0.38 7.797 ± 0.472
AFF3 rs42275280 CC 0.011 84.288 ± 0.382 -0.992 ± 0.417* -2.594 ± 1.999 6.691 ± 0.242 -0.238 ± 0.112* -0.271 ± 0.577
AFF3 rs42275280 CT 82.687 ± 0.382 6.658 ± 0.576
AFF3 rs42275280 TT 86.272 ± 0.382 7.167 ± 0.13
ERCC5 rs133716845 CC 0.031 85.967 ± 0.38 -0.598 ± 0.34 1.054 ± 0.419* 7.098 ± 0.144 0.019 ± 0.096 0.066 ± 0.119
ERCC5 rs133716845 TC 86.423 ± 0.38 7.182 ± 0.141
ERCC5 rs133716845 TT 84.771 ± 0.38 7.135 ± 0.205
MAPK15 rs110323635 AA 0.047 85.592 ± 0.382 0.811 ± 0.33* -0.228 ± 0.403 6.957 ± 0.148 0.185 ± 0.091* 0.055 ± 0.114
MAPK15 rs110323635 GA 86.175 ± 0.382 7.196 ± 0.138
MAPK15 rs110323635 GG 87.213 ± 0.382 7.326 ± 0.192
TG rs133269500 AA 0.02 82.153 ± 0.379 -2.021 ± 0.731** 1.59 ± 0.798* 6.736 ± 0.437 -0.214 ± 0.212 0.073 ± 0.232
TG rs133269500 GA 85.765 ± 0.379 7.024 ± 0.165
TG rs133269500 GG 86.195 ± 0.379 7.165 ± 0.131
ELMOD1 rs42235500 AA 85.947 ± 0.382 -0.039 ± 0.287 0.502 ± 1.095 0.043 6.751 ± 0.192 -0.2 ± 0.081* 0.25 ± 0.301
ELMOD1 rs42235500 GA 86.488 ± 0.382 7.202 ± 0.314
ELMOD1 rs42235500 GG 86.025 ± 0.382 7.151 ± 0.129
UGT3A1 rs42345570 AA 85.329 ± 0.381 -0.278 ± 0.455 0.747 ± 0.512 0.027 7.009 ± 0.255 0.001 ± 0.124 0.292 ± 0.143*
UGT3A1 rs42345570 CA 86.354 ± 0.381 7.3 ± 0.142
UGT3A1 rs42345570 CC 85.884 ± 0.381 7.006 ± 0.14
SLC45A2 rs134604394 AA 86.476 ± 0.382 0.406 ± 0.348 0.081 ± 0.397 7.012 ± 0.185 -0.05 ± 0.097 0.128 ± 0.112
SLC45A2 rs134604394 AT 86.151 ± 0.382 7.191 ± 0.137
SLC45A2 rs134604394 TT 85.664 ± 0.382 7.113 ± 0.161
PCSK6 rs43020736 CC 0.027 86.725 ± 0.38 -0.824 ± 0.319* 0.336 ± 0.383 7.09 ± 0.16 -0.041 ± 0.09 0.183 ± 0.109
PCSK6 rs43020736 TC 86.237 ± 0.38 7.232 ± 0.142
PCSK6 rs43020736 TT 85.078 ± 0.38 7.009 ± 0.169
C27H8orf40 rs135814528 AA 0.009 85.856 ± 0.379 1.856 ± 2.012 0.175 ± 2.098 0.036 7.117 ± 0.128 -1.284 ± 0.564* 1.505 ± 0.589*
C27H8orf40 rs135814528 GA 87.887 ± 0.379 7.338 ± 0.215
C27H8orf40 rs135814528 GG 89.569 ± 0.379 4.549 ± 1.132

1rs# = a reference SNP ID number assigned by National Center for Biotechnology Information (NCBI).

2a = Additive effect of SNP.

3d = Dominance effect of SNP.

*is significant at P < 0.05; **is significant at P < 0.01.